{"id":692021,"date":"2023-01-13T18:30:27","date_gmt":"2023-01-14T02:30:27","guid":{"rendered":"https:\/\/chinadigitaltimes.net\/chinese\/?p=692021"},"modified":"2023-01-13T18:02:05","modified_gmt":"2023-01-14T02:02:05","slug":"%e8%99%8e%e5%97%85app%ef%bd%9c%e5%9b%b4%e5%89%bf%e8%be%89%e7%91%9ep%e8%8d%af","status":"publish","type":"post","link":"https:\/\/chinadigitaltimes.net\/chinese\/692021.html","title":{"rendered":"\u864e\u55c5APP\uff5c\u201c\u56f4\u527f\u201d\u8f89\u745eP\u836f"},"content":{"rendered":"<p><img decoding=\"async\" src=\"https:\/\/chinadigitaltimes.net\/chinese\/files\/2023\/01\/image-1673659829343.png\" alt=\"file\" \/><\/p>\n<div style=\"width:42%;float:right;padding-left:20px\">\n<div class=\"su-spoiler su-spoiler-style-fancy su-spoiler-icon-chevron-circle\" data-scroll-offset=\"0\" data-anchor-in-url=\"no\"><div class=\"su-spoiler-title\" tabindex=\"0\" role=\"button\"><span class=\"su-spoiler-icon\"><\/span>CDT \u6863\u6848\u5361<\/div><div 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u97e6<\/strong>\uff08\u864e\u55c5\u6ce8\uff1a\u5948\u739b\u7279\u97e6\u662fPaxlovid\u6709\u6548\u6210\u5206\uff09\u201d\uff0c\u8fd8\u201c\u6709\u671b\u514b\u670d\u5948\u739b\u7279\u97e6\u5fc5\u987b\u4e0e\u5229\u6258\u90a3\u97e6\u8054\u7528\u7684\u7f3a\u9677\u201d\u3002<\/p>\n<p>\u5b9e\u9645\u4e0a\uff0c\u5728\u4e3b\u6d41\u9776\u70b9\u4e4b\u5916\uff0cJAK\u6291\u5236\u5242\u3001\u5fae\u7ba1\u86cb\u767d\u6291\u5236\u5242\u3001\u96c4\u6fc0\u7d20\u53d7\u4f53\u62ee\u6297\u5242\u7b49\u4e5f\u90fd\u6709\u4ea7\u54c1\u5728\u7814\u3002\u5176\u4e2d\uff0cJAK\u6291\u5236\u5242\u9886\u57df\uff0c\u5df2\u6709\u7f8e\u56fdIncyte\u5f00\u53d1\u7684\u5df4\u745e\u66ff\u5c3c\uff0c\u4e14\u5df2\u7ecf\u83b7\u6279\u7528\u4e8e\u91cd\u75c7\u6cbb\u7597\u3002\u4e16\u536b\u7ec4\u7ec7WHO\u7684\u7528\u836f\u63a8\u8350\u4e2d\uff0c\u4e5f\u5c06\u8be5\u836f\u4e0e\u7cd6\u76ae\u8d28\u6fc0\u7d20\u3001IL-6\u53d7\u4f53\u62ee\u6297\u5242\u88ab\u5217\u4e3a\u91cd\u578b\u548c\u5371\u91cd\u578b\u60a3\u8005\u7684\u201c\u5f3a\u70c8\u63a8\u8350\u201d\u836f\u3002<\/p>\n<p>\u5f53\u7136\uff0c\u5df4\u745e\u66ff\u5c3c\u4e0d\u662f\u6297\u75c5\u6bd2\u7684\uff0c\u662f\u5bf9\u6297\u4eba\u4f53\u514d\u75ab\u53cd\u5e94\u8fdb\u800c\u6291\u5236\u708e\u75c7\u98ce\u66b4\u7684\u4e00\u79cd\u836f\u7269\u3002\u76ee\u524d\u56fd\u5185\u4e5f\u6709\u6cfd\u666f\u5236\u836f\u5728\u8ddf\u8fdb\u7814\u53d1\uff0c\u4ed6\u4eec\u7684\u76d0\u9178\u6770\u514b\u66ff\u5c3c\u5c31\u4e0e\u5df4\u745e\u66ff\u5c3c\u5177\u6709\u7c7b\u4f3c\u7684\u4f5c\u7528\u673a\u5236\u3002<\/p>\n<p>\u53ef\u4ee5\u8bf4\uff0c<strong>\u4e09\u5e74\u6765\uff0c\u4e2d\u56fd\u5728\u65b0\u51a0\u5c0f\u5206\u5b50\u836f\u7269\u7814\u53d1\u9886\u57df\u4e00\u76f4\u662f\u7d27\u7d27\u8ddf\u968f\u7684\u72b6\u6001\u3002<\/strong><\/p>\n<p>\u800c1\u67088\u65e5\u56fd\u5bb6\u533b\u4fdd\u5c40\u5b98\u5ba3\u4e0e\u8f89\u745e\u8c08\u5224\u5931\u8d25\uff0cP\u836f\u672a\u80fd\u5927\u5e45\u964d\u4ef7\u8fdb\u5165\u56fd\u5bb6\u533b\u4fdd\u76ee\u5f55\uff0c\u4e5f\u7ed9\u8fd9\u4e9b\u56fd\u4ea7\u836f\u540e\u6765\u8005\u7559\u51fa\u4e86\u673a\u4f1a\u3002<\/p>\n<p><strong>\u5728\u8fd9\u51e0\u6761\u4e3b\u6d41\u7814\u53d1\u8def\u7ebf\u4e2d\uff0c\u6700\u540e\u5c06\u4f1a\u6709\u54ea\u4e9b\u56fd\u4ea7\u836f\u8dd1\u51fa\u6765\uff1f\u5e0c\u671b\u53c8\u6709\u591a\u5927\uff1f<\/strong><\/p>\n<h3>\u4e3b\u8981\u6280\u672f\u8def\u7ebf\u56fd\u4ea7\u65b0\u51a0\u5c0f\u5206\u5b50\u836f\u57fa\u672c\u4fe1\u606f\uff08\u4e0d\u5b8c\u5168\u7edf\u8ba1\uff09<\/h3>\n<p><strong>\u2193\u2193\u2193<\/strong><\/p>\n<table>\n<thead>\n<tr>\n<th>\u4f5c\u7528\u9776\u70b9\/\u4f5c\u7528\u673a\u5236<\/th>\n<th>\u4ea7\u54c1\u540d\u79f0\/\u4ee3\u53f7<\/th>\n<th>\u4f01\u4e1a\u540d\u79f0<\/th>\n<th>\u8fdb\u5ea6<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>3C L\u86cb\u767d\u9176\u6291\u5236\u5242<\/td>\n<td>\u5148\u8bfa\u6b23\u2122\uff08SIM0417\uff09<\/td>\n<td>\u5357\u4eac\u5148\u58f0<\/td>\n<td>II\/III\u671f\u4e34\u5e8a\u7814\u7a76\u5df2\u5b8c\u6210\u5168\u90e81208\u4f8b\u60a3\u8005\u5165\u7ec4\uff0c\u662f\u56fd\u51853CL\u9776\u70b9\u53e3\u670d\u5c0f\u5206\u5b50\u836f\u7269\u8fdb\u5ea6\u6700\u5feb\u7684\u9879\u76ee\u3002<\/td>\n<\/tr>\n<tr>\n<td>3CL\u86cb\u767d\u9176 \u6291\u5236\u5242<\/td>\n<td>RAY1216<\/td>\n<td>\u4f17\u751f\u836f\u4e1a<\/td>\n<td>\u6b63\u5728\u8fdb\u884c\u2162\u671f\u4e34\u5e8a\u7814\u7a76\u3002<\/td>\n<\/tr>\n<tr>\n<td>3CL\u86cb\u767d\u9176\u6291\u5236  \u5242<\/td>\n<td>FB2001\uff08\u96fe\u5316\u5438\u5165\uff09<\/td>\n<td>\u524d\u6cbf\u751f\u7269<\/td>\n<td>2022\u5e7411\u670823\u65e5\uff0c\u62df\u7528\u4e8e\u6cbb\u7597\u8f7b\u578b\u3001\u666e\u901a\u578b\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\uff08SARSCoV-2\uff09\u611f\u67d3\u60a3\u8005\u7684\u2161\/\u2162\u4e34\u5e8a\u8bd5\u9a8c\u65b9\u6848\uff0c\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\u540c\u610f\u3002<\/td>\n<\/tr>\n<tr>\n<td>3CL\u86cb\u767d\u9176\u6291\u5236 \u5242<\/td>\n<td>EDDC-2214<\/td>\n<td>\u4e91\u9876\u65b0\u8000<\/td>\n<td>\u4e34\u5e8a\u524d\u3002<\/td>\n<\/tr>\n<tr>\n<td>3CL \u86cb\u767d\u9176\u6291\u5236\u5242<\/td>\n<td>ASC11<\/td>\n<td>\u6b4c\u793c\u5236\u836f<\/td>\n<td>2022\u5e7411\u6708\u4efd\u62ff\u5230FDA\u4e34\u5e8a\u6279\u4ef6\uff1b11\u6708\u5e95\u4e2d\u56fd\u56fd\u5bb6\u836f\u76d1\u5c40\u53d7\u7406\u5176\u4e34\u5e8a\u7533\u8bf7\u3002<\/td>\n<\/tr>\n<tr>\n<td>3CL\u86cb\u767d\u9176\u6291 \u5236\u5242<\/td>\n<td>SAL0133<\/td>\n<td>\u4fe1\u7acb\u6cf0<\/td>\n<td>1\u67084\u65e5\u62ff\u5230\u4e34\u5e8a\u6279\u4ef6\uff0c\u5f00\u5c55\u9488\u5bf9\u6210\u4eba\u8f7b\u578b\u3001\u666e\u901a\u578b\u65b0\u51a0\u9002\u5e94\u75c71\u671f\u8bd5\u9a8c\u3002<\/td>\n<\/tr>\n<tr>\n<td>3 CL\u86cb\u767d\u9176\u6291\u5236\u5242<\/td>\n<td>SYH2055<\/td>\n<td>\u77f3\u836f\u96c6\u56e2<\/td>\n<td>\u521a\u62ff\u5230\u4e34\u5e8a\u6279\u4ef6\u3002<\/td>\n<\/tr>\n<tr>\n<td>3CL\u86cb\u767d \u9176\u6291\u5236\u5242<\/td>\n<td>GS221<\/td>\n<td>\u8fdc\u5927\u533b\u836f<\/td>\n<td>\u62ff\u5230\u4e34\u5e8a\u6279\u4ef6\u5e76\u5f00\u5c55\u591a\u9879\u8bd5\u9a8c\u3002<\/td>\n<\/tr>\n<tr>\n<td>3CL\u86cb\u767d\u9176\u6291\u5236\u5242<\/td>\n<td>GST-HG171<\/td>\n<td>\u5e7f\u751f\u5802<\/td>\n<td>II\/III\u671f2022\u5e7412\u670821\u65e5\u5f00\u59cb\u7ed9\u836f\u3002<\/td>\n<\/tr>\n<tr>\n<td>RdRp\u6291\u5236\u5242<\/td>\n<td>\u963f\u5179\u592b\u5b9a<\/td>\n<td>\u771f\u5b9e\u751f\u7269<\/td>\n<td>2022\u5e747\u6708\uff0c\u5728\u4e2d\u56fd\u9644\u6761\u4ef6\u6279\u51c6\u4e0a\u5e02\u3002<\/td>\n<\/tr>\n<tr>\n<td>RdRp \u6291\u5236\u5242<\/td>\n<td>VV116<\/td>\n<td>\u541b\u5b9e\u751f\u7269<\/td>\n<td>\u5728\u4e2d\u56fd\u5904\u4e8e\u4e0a\u5e02\u524d\u6c9f\u901a\u9636\u6bb5\u3002\u4e4c\u5179\u522b\u514b\u65af\u5766\u83b7\u7d27\u6025\u6388\u6743\u4f7f\u7528\u3002<\/td>\n<\/tr>\n<tr>\n<td>RdRp\u6291 \u5236\u5242<\/td>\n<td>ASC10<\/td>\n<td>\u6b4c\u793c\u5236\u836f<\/td>\n<td>1\u671f\u4e34\u5e8a\u9636\u6bb5\u3002<\/td>\n<\/tr>\n<tr>\n<td>RdRp\u6291\u5236 \u5242<\/td>\n<td>SHEN26<\/td>\n<td>\u79d1\u5174\u5236\u836f<\/td>\n<td>2023\u5e741\u67082\u65e5\uff0cII\u671f\u4e34\u5e8a\u7814\u7a76\u5df2\u5b8c\u6210\u5168\u90e8\u53d7\u8bd5\u8005\u5165\u7ec4\u3002<\/td>\n<\/tr>\n<tr>\n<td>RdR p\u6291\u5236\u5242<\/td>\n<td>\u83ab\u90a3\u5339\u62c9\u97e6<\/td>\n<td>\u5b89\u5fbd\u8d1d\u514b\u836f\u4e1a<\/td>\n<td>\u9ed8\u6c99\u4e1c\u83ab\u8bfa\u62c9\u97e6\u7684\u4eff\u5236\u836f\uff0c\u7b49\u5f85\u5ba1\u6279\u4e0a\u5e02\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"font-size: 0.8em;color: #666;display: block;text-align: center;margin-bottom:32px; margin-top: -20px;line-height:22px;\">\u6ce8\uff1a\u6570\u636e\u6765\u81ea\u5404\u516c\u53f8\u516c\u5f00\u4fe1\u606f  \u864e\u55c5\u5236\u56fe<\/p>\n<h2>\u6ede\u540e\u7684\u201c\u4e2d\u56fd\u961f\u201d\u594b\u8d77\u76f4\u8ffd<\/h2>\n<p>\u65b0\u51a0\u5c0f\u5206\u5b50\u836f\u7684\u5e02\u573a\u6b63\u9762\u4e34\u6025\u5267\u7684\u53d8\u5316\u3002<\/p>\n<p>2022\u5e7411\u6708\uff0c\u65e5\u672c\u76d0\u91ce\u4e49\u5236\u836f\u7684Xocova\u4e5f\u5728\u65e5\u672c\u83b7\u5f97\u4e86\u7d27\u6025\u6279\u51c6\u3002\u8fd9\u6b3e\u836f\u4e5f\u5c5e\u4e8e3CL\u86cb\u767d\u9176\u6291\u5236\u5242\uff0c\u4e3b\u8981\u7528\u4e8e\u8f7b\u75c7\u60a3\u8005\u3002\u8fd9\u662f\u5168\u7403\u83b7\u6279\u4e0a\u5e02\u7684\u7b2c\u4e8c\u6b3e3CL\u86cb\u767d\u9176\u6291\u5236\u5242\uff0c\u4e5f\u662f\u7b2c\u4e09\u6b3e\u963b\u65ad\u75c5\u6bd2\u590d\u5236\u3001\u9632\u91cd\u75c7\u7684\u5c0f\u5206\u5b50\u836f\u3002\u5168\u7403\u65b0\u51a0\u5c0f\u5206\u5b50\u836f\u5e02\u573a\u7ade\u4e89\u53c8\u589e\u538b\u529b\u3002<\/p>\n<p>\u540c\u65f6\uff0c\u4e2d\u56fd\u7684\u75ab\u60c5\u4e5f\u6b63\u5728\u50ac\u719f\u56fd\u4ea7\u65b0\u51a0\u5c0f\u5206\u5b50\u836f\u3002\u591a\u4f4d\u533b\u836f\u884c\u4e1a\u4eba\u58eb\u5411\u864e\u55c5\u8868\u793a\uff0c\u5f00\u53d13CL\u86cb\u767d\u9176\u6291\u5236\u5242\u7684\u6280\u672f\u95e8\u69db\u5e76\u4e0d\u9ad8\uff0c\u201cP\u836f\u4e0d\u662f\u4ec0\u4e48\u65b0\u9c9c\u5f97\u4e0d\u5f97\u4e86\u7684\u836f\u201d\u3002\u4e00\u4f4d\u4e1a\u5185\u4eba\u58eb\u8868\u793a\u3002<\/p>\n<p>\u4ece\u5b9e\u9645\u60c5\u51b5\u770b\uff0c\u4e2d\u56fd\u836f\u4f01\u5bf93CL\u6291\u5236\u5242\u7684\u5e03\u5c40\u786e\u5b9e\u4e5f\u6709\u5f00\u82b1\u7ed3\u679c\u7684\u5e0c\u671b\u3002<\/p>\n<p>2022\u5e74\u5e95\uff0c\u5404\u5730\u75ab\u60c5\u9646\u7eed\u8d77\u6b65\u7684\u65f6\u5019\uff0c\u521b\u65b0\u836f\u4f01\u4e1a\u6bd4\u8f83\u96c6\u4e2d\u7684\u6c5f\u82cf\u7701\u5c31\u7ec4\u7ec7\u5f53\u5730\u4f01\u4e1a\u5f00\u201c\u8c03\u5ea6\u4f1a\u201d\u3002\u6c5f\u82cf\u7701\u836f\u76d1\u5c40\u900f\u9732\uff0c\u5148\u58f0\u836f\u4e1a\u4e0e\u4e2d\u56fd\u79d1\u5b66\u9662\u4e0a\u6d77\u836f\u7269\u7814\u7a76\u6240\u3001\u6b66\u6c49\u75c5\u6bd2\u7814\u7a76\u6240\u8054\u5408\u5f00\u53d1\u7684SIM0417\uff0c\u5c06\u4e8e2023\u5e742\u6708\u4e0a\u5e02\u3002\u8fd9\u4e5f\u662f\u4e2d\u56fd\u8fdb\u5c55\u6700\u5feb\u76843CL\u9776\u70b9\u836f\u7269\u3002<\/p>\n<p>\u540c\u6837\u901f\u5ea6\u8f83\u5feb\u7684\u4f17\u751f\u836f\u4e1aRAY1216\uff0c\u4e00\u79cd3CL\u86cb\u767d\u9176\u6291\u5236\u5242\u4e5f\u5df2\u7ecf\u542f\u52a8\u4e86\u4e09\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002\u6839\u636e\u516c\u53f8\u516c\u5f00\u4fe1\u606f\uff0c\u8be5\u836f\u751a\u81f3\u6709\u6210\u4e3a\u201c\u6700\u4f73\u65b0\u51a0\u53e3\u670d\u836f\u7684\u6f5c\u529b\u201d\u3002<\/p>\n<p>RdRp\u6291\u5236\u5242\u8d5b\u9053\u4e5f\u4e0d\u7518\u843d\u540e\u300212\u670829\u65e5\uff0c\u300a\u65b0\u82f1\u683c\u5170\u533b\u5b66\u6742\u5fd7\u300b\uff08NEJM\uff09\u520a\u53d1\u4e86\u4e2d\u56fd\u65b0\u51a0\u53e3\u670d\u836fVV116\u4e0ePaxlovid\u201c\u5934\u5bf9\u5934\u201d\u8bd5\u9a8c\u7684\u7ed3\u679c\uff0c\u7ed3\u679c\u8868\u660eVV116\u7597\u6548\u975e\u52a3\u6027\uff0c\u4e14\u5b89\u5168\u6027\u66f4\u597d\u3002<\/p>\n<p>\u8fd8\u6709\u4e00\u4e9b\u201c\u540e\u8d77\u4e4b\u79c0\u201d\u30022023\u5e741\u67087\u65e5\uff0c\u5e7f\u751f\u5802\u53c8\u53d1\u51fa\u516c\u544a\uff0c\u516c\u5e03\u4e00\u9879\u4e0d\u8d85\u8fc79.48\u4ebf\u5143\u7684\u878d\u8d44\u8ba1\u5212\uff0c\u5176\u4e2d\u5c31\u5305\u62ec\u4e86\u4e00\u6b3e\u65b0\u51a0\u53e3\u670d\u5c0f\u5206\u5b50\u836f\u7684\u7814\u53d1\uff08\u4ee3\u53f7\uff1aGST-HG171\uff09\uff0c\u8fd9\u4e5f\u662f\u6b3e3CL\u86cb\u767d\u9176\u6291\u5236\u5242\uff0c\u65e9\u57289\u6708\u4efd\u5c31\u62ff\u5230\u4e86\u4e34\u5e8a\u6279\u4ef6\u3002<\/p>\n<p>\u864e\u55c5\u67e5\u8be2\u4e2d\u56fd\u4e34\u5e8a\u8bd5\u9a8c\u6ce8\u518c\u4e2d\u5fc3\u6570\u636e\u53d1\u73b0\uff0c2022\u5e74\u768412\u670826\u65e5\u300127\u65e5\uff0c\u6709\u4e24\u9879\u8bc4\u4f30GST-HG171\u5bf9\u65b0\u51a0\u611f\u67d3\u8005\u5b89\u5168\u6027\u6709\u6548\u6027\u7684\u8bd5\u9a8c\u5728\u7ebf\u4e0a\u6ce8\u518c\u3002<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/chinadigitaltimes.net\/chinese\/files\/2023\/01\/post-692021-63c20d1d9c30d.png\" alt=\"image\" \/><br \/>\n<p style=\"font-size: 0.8em;color: #666;display: block;text-align: center;margin-bottom:32px; margin-top: 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